Protein Details: Gap junction alpha-5 protein

Protein ID

ICDB_Pro_0508

Protein Name

Gap junction alpha-5 protein

Gene Name

GJA5

Organism

Homo sapiens (Human)

Length

358 amino acids

AlphaFoldDB

AF-P36382-F1-model_v4.pdb

Function

Sequence

MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQVRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Atrial Fibrillation;Familial;11 and Atrial Standstill 1

Location

DOI ID

10.1006/jmcc.1994.1103; 10.1053/euhj.1999.1718; 10.1038/nature04727; 10.1101/gr.2596504; 10.1056/nejmoa052800; 10.1093/europace/euq274

RefSeq

NP_005257.2; NP_859054.1; XP_005273008.1; XP_016856533.1